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Sermorelin was previously FDA-approved under the brand name Geref, both as a diagnostic agent for GH deficiency (Geref Diagnostic, approved 1997) and as a therapeutic agent for pediatric idiopathic GH deficiency

But the gastrointestinal effects are unpleasant enough that many people discontinue within the first few months

Both peptides are known for having minimal side effects

The generation of antibody-secreting plasma cells